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mubritinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View mubritinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	mubritinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CSRP2 Gene (Entity type)	-0.008101454
	mubritinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Receptor tyrosine-protein kinase erbB-2 Protein (Entity type)	IC50
	mubritinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FABP7 Gene (Entity type)	-0.008747075
	mubritinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FABP4 Gene (Entity type)	0.008512292
	mubritinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ASPN Gene (Entity type)	0.011419663
	mubritinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IKZF1 Gene (Entity type)	-0.008021069
	mubritinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Temoporfin Compound (Entity type)	0.3295459151268005
	mubritinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LTF Gene (Entity type)	-0.013898237
	mubritinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GNA15 Gene (Entity type)	-0.00983602
	mubritinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MN1 Gene (Entity type)	0.008389064

mubritinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CSRP2
Gene (Entity type)
-0.008101454

mubritinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Receptor tyrosine-protein kinase erbB-2
Protein (Entity type)
IC50

mubritinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FABP7
Gene (Entity type)
-0.008747075

mubritinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FABP4
Gene (Entity type)
0.008512292

mubritinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ASPN
Gene (Entity type)
0.011419663

mubritinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IKZF1
Gene (Entity type)
-0.008021069

mubritinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Temoporfin
Compound (Entity type)
0.3295459151268005

mubritinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LTF
Gene (Entity type)
-0.013898237

mubritinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GNA15
Gene (Entity type)
-0.00983602

mubritinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MN1
Gene (Entity type)
0.008389064

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