3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	C2CD2 Gene (Entity type)	-0.005786226
3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TGFBR2 Gene (Entity type)	-0.0071254806
3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMOX1 Gene (Entity type)	-0.0058889757
3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SRC Gene (Entity type)	0.0070550586
3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RPS4Y1 Gene (Entity type)	-0.0064699817
3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PKP2 Gene (Entity type)	-0.0057707955
3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RGS1 Gene (Entity type)	-0.005681309
3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	THBD Gene (Entity type)	-0.005610093
3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TFPI Gene (Entity type)	-0.0060366667
3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RNF167 Gene (Entity type)	0.007156586

3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
C2CD2
Gene (Entity type)
-0.005786226

3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TGFBR2
Gene (Entity type)
-0.0071254806

3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMOX1
Gene (Entity type)
-0.0058889757

3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SRC
Gene (Entity type)
0.0070550586

3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RPS4Y1
Gene (Entity type)
-0.0064699817

3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PKP2
Gene (Entity type)
-0.0057707955

3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RGS1
Gene (Entity type)
-0.005681309

3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
THBD
Gene (Entity type)
-0.005610093

3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TFPI
Gene (Entity type)
-0.0060366667

3-((4aR,12aR)-2,12a-dimethyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RNF167
Gene (Entity type)
0.007156586

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