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Chlorthalidone (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Chlorthalidone's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Chlorthalidone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF3 Gene (Entity type)	-0.005167461
	Chlorthalidone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NEBL Gene (Entity type)	-0.004124389
	Chlorthalidone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AQP3 Gene (Entity type)	0.0049193026
	Chlorthalidone Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Carbonic anhydrase 5A, mitochondrial Protein (Entity type)	Ki
	Chlorthalidone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CD93 Gene (Entity type)	0.004222305
	Chlorthalidone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LIMCH1 Gene (Entity type)	-0.004335238
	Chlorthalidone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NELL2 Gene (Entity type)	0.0040061353
	Chlorthalidone Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Carbonic anhydrase 9 Protein (Entity type)	Ki
	Chlorthalidone Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Edema Disease or Phenotype (Entity type)
	Chlorthalidone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RBM34 Gene (Entity type)	0.004242488

Chlorthalidone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ATF3
Gene (Entity type)
-0.005167461

Chlorthalidone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NEBL
Gene (Entity type)
-0.004124389

Chlorthalidone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AQP3
Gene (Entity type)
0.0049193026

Chlorthalidone
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Carbonic anhydrase 5A, mitochondrial
Protein (Entity type)
Ki

Chlorthalidone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CD93
Gene (Entity type)
0.004222305

Chlorthalidone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LIMCH1
Gene (Entity type)
-0.004335238

Chlorthalidone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NELL2
Gene (Entity type)
0.0040061353

Chlorthalidone
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Carbonic anhydrase 9
Protein (Entity type)
Ki

Chlorthalidone
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Edema
Disease or Phenotype (Entity type)

Chlorthalidone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RBM34
Gene (Entity type)
0.004242488

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