[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View [4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	PT-630 Compound (Entity type)	0.2936356365680694
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NEBL Gene (Entity type)	-0.009055511
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLBD1 Gene (Entity type)	0.006153999
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	INSM1 Gene (Entity type)	-0.007874461
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FXYD3 Gene (Entity type)	-0.012076809
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAP7 Gene (Entity type)	-0.008392634
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT7 Gene (Entity type)	-0.008168281
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	C7 Gene (Entity type)	0.008293669
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Benign Prostatic Hyperplasia Disease or Phenotype (Entity type)
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AGR2 Gene (Entity type)	-0.009217205

[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
PT-630
Compound (Entity type)
0.2936356365680694

[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NEBL
Gene (Entity type)
-0.009055511

[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLBD1
Gene (Entity type)
0.006153999

[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
INSM1
Gene (Entity type)
-0.007874461

[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FXYD3
Gene (Entity type)
-0.012076809

[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MAP7
Gene (Entity type)
-0.008392634

[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT7
Gene (Entity type)
-0.008168281

[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
C7
Gene (Entity type)
0.008293669

[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Benign Prostatic Hyperplasia
Disease or Phenotype (Entity type)

[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-(tetrahydro-furan-2-yl)-methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AGR2
Gene (Entity type)
-0.009217205

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Knowledge Graph Assertions

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