6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF3 Gene (Entity type)	-0.005984295
6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DDX42 Gene (Entity type)	-0.0049036494
6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EBP Gene (Entity type)	0.006820036
6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CRYBG1 Gene (Entity type)	0.0069316095
6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RGCC Gene (Entity type)	-0.0056338743
6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BTG3 Gene (Entity type)	-0.0058166524
6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GCLM Gene (Entity type)	-0.005799891
6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	SA-1921456 Compound (Entity type)	0.5416269302368164
6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AKR1C2 Gene (Entity type)	-0.0069158766
6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	0.014864771

6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ATF3
Gene (Entity type)
-0.005984295

6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DDX42
Gene (Entity type)
-0.0049036494

6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EBP
Gene (Entity type)
0.006820036

6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CRYBG1
Gene (Entity type)
0.0069316095

6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RGCC
Gene (Entity type)
-0.0056338743

6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BTG3
Gene (Entity type)
-0.0058166524

6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GCLM
Gene (Entity type)
-0.005799891

6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
SA-1921456
Compound (Entity type)
0.5416269302368164

6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AKR1C2
Gene (Entity type)
-0.0069158766

6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HMGCS1
Gene (Entity type)
0.014864771

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.