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bupropion (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View bupropion's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	bupropion Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GUCY1B1 Gene (Entity type)	0.0031544962
	bupropion Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NUSAP1 Gene (Entity type)	0.00594303
	bupropion Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFITM1 Gene (Entity type)	-0.003287285
	bupropion Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALOX5 Gene (Entity type)	0.003220368
	bupropion Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	-0.0032549275
	bupropion Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	miglustat Compound (Entity type)	0.4320728182792663
	bupropion Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ZFP36L2 Gene (Entity type)	-0.0032805575
	bupropion Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Nicotine Dependence Disease or Phenotype (Entity type)
	N-{2-Butyl-3-[4-(3-dibutylamino-propoxy)-benzoyl]-benzofuran-5-yl}-methanesulfonamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	bupropion Compound (Entity type)	0.4127234518527984
	bupropion Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TBC1D9 Gene (Entity type)	0.0034256114

bupropion
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GUCY1B1
Gene (Entity type)
0.0031544962

bupropion
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NUSAP1
Gene (Entity type)
0.00594303

bupropion
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFITM1
Gene (Entity type)
-0.003287285

bupropion
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALOX5
Gene (Entity type)
0.003220368

bupropion
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
S100A8
Gene (Entity type)
-0.0032549275

bupropion
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
miglustat
Compound (Entity type)
0.4320728182792663

bupropion
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ZFP36L2
Gene (Entity type)
-0.0032805575

bupropion
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Nicotine Dependence
Disease or Phenotype (Entity type)

N-{2-Butyl-3-[4-(3-dibutylamino-propoxy)-benzoyl]-benzofuran-5-yl}-methanesulfonamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
bupropion
Compound (Entity type)
0.4127234518527984

bupropion
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TBC1D9
Gene (Entity type)
0.0034256114

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