1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NID2 Gene (Entity type)	-0.005820898
1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAT Gene (Entity type)	0.0065108966
1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DNM1L Gene (Entity type)	0.0059293536
1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PAN2 Gene (Entity type)	-0.0050040823
1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(2R,3R,4S,5R)-2-(6-(furan-2-ylmethylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol Compound (Entity type)	0.3133660852909088
1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCN3 Gene (Entity type)	-0.005372805
1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GPRC5A Gene (Entity type)	0.007380046
1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MCOLN1 Gene (Entity type)	-0.005617808
1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	F2RL1 Gene (Entity type)	0.008182427
1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	prostratin Compound (Entity type)	0.3836542963981628

1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NID2
Gene (Entity type)
-0.005820898

1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAT
Gene (Entity type)
0.0065108966

1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DNM1L
Gene (Entity type)
0.0059293536

1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PAN2
Gene (Entity type)
-0.0050040823

1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(2R,3R,4S,5R)-2-(6-(furan-2-ylmethylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Compound (Entity type)
0.3133660852909088

1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCN3
Gene (Entity type)
-0.005372805

1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GPRC5A
Gene (Entity type)
0.007380046

1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MCOLN1
Gene (Entity type)
-0.005617808

1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
F2RL1
Gene (Entity type)
0.008182427

1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
prostratin
Compound (Entity type)
0.3836542963981628

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.