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Cyclizine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Cyclizine's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Cyclizine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	0.0041032345
	Cyclizine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TACC2 Gene (Entity type)	0.0040457603
	Cyclizine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CSTA Gene (Entity type)	-0.004983143
	Cyclizine Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Hay fever Disease or Phenotype (Entity type)
	Cyclizine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CA2 Gene (Entity type)	-0.004914904
	Cyclizine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Histamine H1 receptor Protein (Entity type)	Ki
	Cyclizine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADD3 Gene (Entity type)	-0.004867051
	Cyclizine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AK4 Gene (Entity type)	-0.0046048295
	Cyclizine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RGS4 Gene (Entity type)	-0.0051879873
	3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Cyclizine Compound (Entity type)	0.4295190870761871

Cyclizine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
0.0041032345

Cyclizine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TACC2
Gene (Entity type)
0.0040457603

Cyclizine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CSTA
Gene (Entity type)
-0.004983143

Cyclizine
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Hay fever
Disease or Phenotype (Entity type)

Cyclizine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CA2
Gene (Entity type)
-0.004914904

Cyclizine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Histamine H1 receptor
Protein (Entity type)
Ki

Cyclizine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADD3
Gene (Entity type)
-0.004867051

Cyclizine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AK4
Gene (Entity type)
-0.0046048295

Cyclizine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RGS4
Gene (Entity type)
-0.0051879873

3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Cyclizine
Compound (Entity type)
0.4295190870761871

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