1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TNFRSF12A Gene (Entity type)	0.009786633
1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DPYSL2 Gene (Entity type)	-0.008357768
1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TSPAN13 Gene (Entity type)	-0.00832434
1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADM Gene (Entity type)	0.010531779
1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCNG1 Gene (Entity type)	-0.008450116
1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	cephaeline Compound (Entity type)	0.7082842588424683
avicin-d Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	0.3104173839092254
Kepone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	0.2927761375904083
1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	JUN Gene (Entity type)	0.011276959
1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CCN1 Gene (Entity type)	0.008531523

1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TNFRSF12A
Gene (Entity type)
0.009786633

1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DPYSL2
Gene (Entity type)
-0.008357768

1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TSPAN13
Gene (Entity type)
-0.00832434

1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADM
Gene (Entity type)
0.010531779

1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCNG1
Gene (Entity type)
-0.008450116

1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
cephaeline
Compound (Entity type)
0.7082842588424683

avicin-d
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
0.3104173839092254

Kepone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
0.2927761375904083

1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
JUN
Gene (Entity type)
0.011276959

1-(1-acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CCN1
Gene (Entity type)
0.008531523

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Knowledge Graph Assertions

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