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Pacritinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Pacritinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Pacritinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KLF2 Gene (Entity type)	-0.010562587
	Pacritinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HPGD Gene (Entity type)	-0.011212653
	Pacritinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DKK1 Gene (Entity type)	-0.010478903
	Pacritinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase STK11 Protein (Entity type)	Kd
	Pacritinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HOXC6 Gene (Entity type)	-0.01340169
	Pacritinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL12 Gene (Entity type)	-0.011336166
	Pacritinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IL17RB Gene (Entity type)	0.010939591
	Pacritinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Uncharacterized protein FLJ45252 Protein (Entity type)	Kd
	Pacritinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SCD Gene (Entity type)	0.014863042
	Pacritinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TARBP1 Gene (Entity type)	0.011480864

Pacritinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KLF2
Gene (Entity type)
-0.010562587

Pacritinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HPGD
Gene (Entity type)
-0.011212653

Pacritinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DKK1
Gene (Entity type)
-0.010478903

Pacritinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase STK11
Protein (Entity type)
Kd

Pacritinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HOXC6
Gene (Entity type)
-0.01340169

Pacritinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CXCL12
Gene (Entity type)
-0.011336166

Pacritinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IL17RB
Gene (Entity type)
0.010939591

Pacritinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Uncharacterized protein FLJ45252
Protein (Entity type)
Kd

Pacritinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SCD
Gene (Entity type)
0.014863042

Pacritinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TARBP1
Gene (Entity type)
0.011480864

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