PR001855 (Project)

Id Namespace:

UCSD Metabolomics Workbench

Identifier Namespace (Entity type)

Dcc Asset:

MW submission packet 20250922.zip

Processed File (Entity type)

Dcc:

Metabolomics

DCC (Entity type)

Persistent Id:http://dx.doi.org/10.21228/M8XT6T

Description:Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder caused by mutations in either TSC1 or TSC2. There's evidence suggests a connection between microglia activation and epilepsy as well as cognitive impairment in TSC patients. However, how the causal variants of TSC1/2 genes identified in TSC patients affect human microglia and how they contribute to the neurological manifestations. This project is focus on this problem using human microglia generated from induced pluripotent stem cells (iPSCs) derived from a TSC patient.

Results found

Linked to

	Label	Description
	PPR00001 Project (Entity type)	Metabolomics
	SU003092 Subject (Entity type)	A subject from Metabolomics produced as part of the PR001855 project
	SU003473 Subject (Entity type)	A subject from Metabolomics produced as part of the PR001855 project
	SA365709 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001855 project
	SA323374 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001855 project
	SA323378 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001855 project
	SA365707 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001855 project
	SA323388 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001855 project
	SA365701 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001855 project
	SA323389 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001855 project

PPR00001

Project (Entity type)

Metabolomics

SU003092

Subject (Entity type)

A subject from Metabolomics produced as part of the PR001855 project

SU003473

Subject (Entity type)

A subject from Metabolomics produced as part of the PR001855 project

SA365709

Biosample (Entity type)