GCP-PCCSE (Project)

Id Namespace:

Library of Integrated Network-Based Cellular Signatures

Identifier Namespace (Entity type)

Dcc Asset:

datapackage.zip

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Description:The LINCS PCCSE uses two high-throughput liquid chromatography-mass spectrometry (LCMS) assays to study the proteomic changes induced by drug and genetic perturbations. GCP monitors ~60 modified peptides from histones (e.g., methylated, acetylated, and combinations thereof) encompassing nearly every well-studied post-translational modification on the core nucleosomal histone proteins. The files available here contain GCP data for 90 small-molecule perturbations in six cell lines (five cancer cell lines and a neurodevelopmental cell model).

Abbreviation:GCP

Results found

Linked to

	Label	Description
	LINCS DCIC GYC-38667 YAPC 24h BMS-345541 1.00uM Biosample (Entity type)	A biosample from LINCS produced as part of the GCP PCCSE project
	LINCS DCIC GYC-13C77 YAPC 24h BIX-01338 10.00uM Biosample (Entity type)	A biosample from LINCS produced as part of the GCP PCCSE project
	LINCS DCIC GA5-30E17 A375 24h methylstat 10.00uM Biosample (Entity type)	A biosample from LINCS produced as part of the GCP PCCSE project
	LINCS DCIC GA5-11373 A375 24h ginkgetin 5.00uM Biosample (Entity type)	A biosample from LINCS produced as part of the GCP PCCSE project
	LINCS DCIC GA9-2C187 A549 24h sotrastaurin 10.00uM Biosample (Entity type)	A biosample from LINCS produced as part of the GCP PCCSE project
	LINCS DCIC GA9-2C187 A549 24h CYT387 1.00uM Biosample (Entity type)	A biosample from LINCS produced as part of the GCP PCCSE project
	LINCS DCIC GA9-2C187 A549 24h 4,5,6,7-tetrabromobenzotriazole 25.00uM Biosample (Entity type)	A biosample from LINCS produced as part of the GCP PCCSE project
	LINCS DCIC GM7-29BA3 MCF7 24h everolimus 0.10uM Biosample (Entity type)	A biosample from LINCS produced as part of the GCP PCCSE project
	LINCS DCIC GM7-33653 MCF7 24h tacrolimus 10.00uM Biosample (Entity type)	A biosample from LINCS produced as part of the GCP PCCSE project
	LINCS DCIC GA9-2EA8C A549 24h CC-401 5.00uM Biosample (Entity type)	A biosample from LINCS produced as part of the GCP PCCSE project