SCGE:18000000107 (Project)

Id Namespace:

Somatic Cell Genome Editing

Identifier Namespace (Entity type)

Dcc Asset:

scge cfde submission 20251016 143304.zip

Processed File (Entity type)

Dcc:

SCGE

DCC (Entity type)

Persistent Id:https://scge.mcw.edu/toolkit/data/experiments/experiment/18000000107

Description:Virus-like particles carrying a CRISPR/Cas base editor and a guide RNA targeting the PSCK9 locus were injected i.v. into male and female mice. One week after injection, the mice were dissected, and genomic DNA isolated from a panel of organs. Targeted NGS was performed to evaluate the degree of editing at the PCSK9 locus in the liver (primary target), and non-target organs. Two potential off-target editing sites (OT6 and OT7) were also sequenced.

Abbreviation:SCGE18000000107

Results found

Linked to

	Label	Description
	SCGE:15000003581 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000107 project
	SCGE:15000003523 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000107 project
	SCGE:15000003522 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000107 project
	SCGE:15000003573 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000107 project
	SCGE:15000003521 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000107 project
	SCGE:15000003536 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000107 project
	SCGE:15000003561 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000107 project
	SCGE:15000003520 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000107 project
	SCGE:15000003544 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000107 project
	SCGE:15000003555 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000107 project