PR001600 (Project)

Description:Severe COVID-19 is characterized by an increase in the number and changes in the function of innate immune cells including neutrophils. However, it is not known how the metabolome of immune cells changes in COVID-19 patients or how metabolic changes may contribute to immune dysfunction. To address these questions, we analyzed the metabolome of neutrophils from patients with severe or mild COVID-19, or healthy controls. We identified widespread dysregulation of neutrophil metabolism with disease progression including in amino acid, redox, and central carbon metabolism.
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Metabolomics

Subject

A subject from Metabolomics produced as part of the PR001600 project

File

A 15.7 GB file from Metabolomics produced from OBI:0003097 as part of the PR001600 project

Biosample

A biosample from Metabolomics produced as part of the PR001600 project

Biosample

A biosample from Metabolomics produced as part of the PR001600 project

Biosample

A biosample from Metabolomics produced as part of the PR001600 project

Biosample

A biosample from Metabolomics produced as part of the PR001600 project

Biosample

A biosample from Metabolomics produced as part of the PR001600 project

Biosample

A biosample from Metabolomics produced as part of the PR001600 project

Biosample

A biosample from Metabolomics produced as part of the PR001600 project


  • Subject

    A subject from Metabolomics produced as part of the PR001600 project


  • File

    A 15.7 GB file from Metabolomics produced from OBI:0003097 as part of the PR001600 project


  • Biosample

    A biosample from Metabolomics produced as part of the PR001600 project


  • Biosample

    A biosample from Metabolomics produced as part of the PR001600 project


  • Biosample

    A biosample from Metabolomics produced as part of the PR001600 project


  • Biosample

    A biosample from Metabolomics produced as part of the PR001600 project


  • Biosample

    A biosample from Metabolomics produced as part of the PR001600 project


  • Biosample

    A biosample from Metabolomics produced as part of the PR001600 project


  • Biosample

    A biosample from Metabolomics produced as part of the PR001600 project

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