ISLR (Gene)

Description: immunoglobulin superfamily containing leucine rich repeat

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ISLR's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ISLR.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ISLR.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ISLR.

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Gene Sets (1200)

LINCS L1000 Chem Pert Consensus Sigs (616)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (5)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (1)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (564)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (7)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
JNJ16259685 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ISLR Gene (Entity type)	0.0074399244
hyoscyamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ISLR Gene (Entity type)	0.0060008476
Acyclovir Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ISLR Gene (Entity type)	0.00371902
trehalose Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ISLR Gene (Entity type)	0.0040046675
Methantheline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ISLR Gene (Entity type)	-0.0077530257
oxolinic-acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ISLR Gene (Entity type)	-0.025853407
isosalsoline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ISLR Gene (Entity type)	0.0167105
SA-424827 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ISLR Gene (Entity type)	0.011485957
PX-12 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ISLR Gene (Entity type)	-0.004940428
sasapyrine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ISLR Gene (Entity type)	0.0040229806