ESR1 (Gene)

Description: estrogen receptor 1

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ESR1's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ESR1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ESR1.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ESR1.

Submit

Gene Sets (2929)

LINCS L1000 Chem Pert Consensus Sigs (1548)

A gene set library provided by LINCS

GlyGen Glycosylated Proteins 2022 (1)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (1333)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (2)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (16)

A gene set library provided by GTEx

IDG Drug Targets 2022 (28)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
IRL-2500 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ESR1 Gene (Entity type)	0.009826463
4-(3'-Fluorophenethyl)-4-azahexacyclo[5.4.1.02,6.03,10.05,9.08,11]dodecan-3-ol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ESR1 Gene (Entity type)	0.008226876
Gedunin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ESR1 Gene (Entity type)	-0.012433362
minodronic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ESR1 Gene (Entity type)	-0.007238532
LY341495 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ESR1 Gene (Entity type)	0.00988205
clonidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ESR1 Gene (Entity type)	0.003966216
N,N''-Bis-[1-(3-fluoro-phenyl)-meth-(E)-ylidene]-hydrazine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ESR1 Gene (Entity type)	0.0065634334
4-acetamido-N-(2-amino-4-fluorophenyl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ESR1 Gene (Entity type)	0.0049554994
leu-enkephalin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ESR1 Gene (Entity type)	0.01237455
spectinomycin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ESR1 Gene (Entity type)	0.0079630865