ADAM10 (Gene)

Description: ADAM metallopeptidase domain 10

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ADAM10's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ADAM10.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ADAM10.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ADAM10.

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Gene Sets (1098)

LINCS L1000 Chem Pert Consensus Sigs (426)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (6)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (661)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
ICI-63197 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADAM10 Gene (Entity type)	-0.0071917786
Y-27152 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADAM10 Gene (Entity type)	0.0037226512
safrolglycol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADAM10 Gene (Entity type)	-0.009868956
KFGENEBIN:ADAM10-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	ADAM10 Gene (Entity type)
HTMT Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADAM10 Gene (Entity type)	-0.009800748
Cyclohexyl-(2-phenoxy-9H-purin-6-yl)-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADAM10 Gene (Entity type)	-0.004688838
homoquinolinic-acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADAM10 Gene (Entity type)	-0.005405694
dubinidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADAM10 Gene (Entity type)	0.01092801
9,10,11,12,tetrahydro-9,12-epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-1,3(2H)-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADAM10 Gene (Entity type)	-0.009203511
PQ401 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADAM10 Gene (Entity type)	0.008759004