ATF4 (Gene)

Description: activating transcription factor 4

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ATF4's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ATF4.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ATF4.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ATF4.

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Gene Sets (1172)

LINCS L1000 Chem Pert Consensus Sigs (740)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (7)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (416)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (4)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
I-606051 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ATF4 Gene (Entity type)	0.023515278
evodiamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF4 Gene (Entity type)	-0.0075909114
MW-MITF9 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF4 Gene (Entity type)	-0.01118259
AMD-3100 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF4 Gene (Entity type)	-0.0042040995
CGP 71683A Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ATF4 Gene (Entity type)	0.02201277
KU-C104337 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ATF4 Gene (Entity type)	0.022694446
AG-370 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF4 Gene (Entity type)	-0.008741363
SA-247654 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF4 Gene (Entity type)	-0.012646899
puromycin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ATF4 Gene (Entity type)	0.018636959
CCCP Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ATF4 Gene (Entity type)	0.007866492