CERK (Gene)

Description: ceramide kinase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CERK's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CERK.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CERK.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CERK.

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Gene Sets (392)

LINCS L1000 Chem Pert Consensus Sigs (131)

A gene set library provided by LINCS

LINCS L1000 CRISPR KO Consensus Sigs (256)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (3)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
CERK Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Cer 18:1;O2/18:0 Metabolite (Entity type)
3,5-dichloro-2-hydroxy-N-(4-methoxy-biphenyl-3-yl)-benzenesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CERK Gene (Entity type)	-0.0065661115
CERK Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Adenosine Diphosphate Metabolite (Entity type)
KFGENEBIN:CERK-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	CERK Gene (Entity type)
dirithromycin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CERK Gene (Entity type)	0.018295346
CERK Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	atp binding Metabolite (Entity type)
CERK Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ATP Metabolite (Entity type)
CERK Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ADP Metabolite (Entity type)
CERK Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Cer 18:1;O2/14:0 Metabolite (Entity type)