TYROBP (Gene)

Description: transmembrane immune signaling adaptor TYROBP

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TYROBP's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TYROBP.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TYROBP.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TYROBP.

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Gene Sets (1223)

LINCS L1000 Chem Pert Consensus Sigs (630)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (16)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (563)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (7)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (6)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
KFGENEBIN:TYROBP-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	TYROBP Gene (Entity type)
DMNB Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TYROBP Gene (Entity type)	0.03371301
suprofen Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TYROBP Gene (Entity type)	-0.0035098547
Bromopride Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TYROBP Gene (Entity type)	-0.03142587
clonixin-lysinate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TYROBP Gene (Entity type)	-0.0047059148
7,8-dihydroxy-6-methoxy-2H-chromen-2-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TYROBP Gene (Entity type)	-0.009786841
(-)-Phenyl-carbamic acid 1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indol-5-yl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TYROBP Gene (Entity type)	0.0068632895
SA-1459430 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TYROBP Gene (Entity type)	0.014932988
VU-0413255-1 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TYROBP Gene (Entity type)	0.011825672
KU-C103874 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TYROBP Gene (Entity type)	0.010892093