HTRA1 (Gene)

Description: HtrA serine peptidase 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HTRA1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HTRA1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HTRA1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HTRA1.

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Gene Sets (2002)

LINCS L1000 Chem Pert Consensus Sigs (610)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (2)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1385)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
enalapril Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HTRA1 Gene (Entity type)	-0.003246017
Fomepizole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HTRA1 Gene (Entity type)	-0.0046430174
Dexfenfluramine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HTRA1 Gene (Entity type)	-0.0043930616
Lopinavir Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HTRA1 Gene (Entity type)	-0.0030036443
AMD-3100 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HTRA1 Gene (Entity type)	-0.0051305275
(E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HTRA1 Gene (Entity type)	-0.003253169
Ellagic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HTRA1 Gene (Entity type)	0.002923531
Iproniazid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HTRA1 Gene (Entity type)	0.006104999
AH-11110 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HTRA1 Gene (Entity type)	0.0052192085
liranaftate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HTRA1 Gene (Entity type)	0.0062982487