TXNIP (Gene)

Entrez Gene ID: 10628

Description: thioredoxin interacting protein

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TXNIP's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with TXNIP.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TXNIP.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TXNIP.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TXNIP.

Gene Sets (5707)

LINCS L1000 Chem Pert Consensus Sigs (1435)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (11)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (8)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (864)

A gene set library provided by LINCS

rummageo gene perturbations (338)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (2)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (760)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1766)

A gene set library provided by LINCS

rummageo chemical perturbations (521)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SID11112313 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TXNIP Gene (Entity type)	-0.003634909
3-[4-(4-Iodo-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TXNIP Gene (Entity type)	-0.009531759
L-161982 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TXNIP Gene (Entity type)	-0.010169818
EMF-sumo1-3 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TXNIP Gene (Entity type)	-0.013631265
SA-1463838 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TXNIP Gene (Entity type)	-0.015129487
MW-A1-12 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TXNIP Gene (Entity type)	-0.0044483873
PETCM Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TXNIP Gene (Entity type)	-0.0043157404
Exisulind Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TXNIP Gene (Entity type)	-0.0067965067
ACDPP Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TXNIP Gene (Entity type)	-0.016697172
Nilotinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TXNIP Gene (Entity type)	-0.003568488

SID11112313
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TXNIP
Gene (Entity type)
-0.003634909

3-[4-(4-Iodo-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TXNIP
Gene (Entity type)
-0.009531759

L-161982
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TXNIP
Gene (Entity type)
-0.010169818

EMF-sumo1-3
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TXNIP
Gene (Entity type)
-0.013631265

SA-1463838
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TXNIP
Gene (Entity type)
-0.015129487

MW-A1-12
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TXNIP
Gene (Entity type)
-0.0044483873

PETCM
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TXNIP
Gene (Entity type)
-0.0043157404

Exisulind
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TXNIP
Gene (Entity type)
-0.0067965067

ACDPP
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TXNIP
Gene (Entity type)
-0.016697172

Nilotinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TXNIP
Gene (Entity type)
-0.003568488

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.