BCKDHA (Gene)

Entrez Gene ID: 593

Description: branched chain keto acid dehydrogenase E1 subunit alpha

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View BCKDHA's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with BCKDHA.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using BCKDHA.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for BCKDHA.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with BCKDHA.

Gene Sets (650)

LINCS L1000 Chem Pert Consensus Sigs (13)

A gene set library provided by LINCS

Metabolomics Workbench Metabolites 2022 (2)

A gene set library provided by MW

KOMP2 Mouse Phenotypes 2022 (4)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (22)

A gene set library provided by LINCS

rummageo gene perturbations (126)

A gene set library provided by LINCS

RummaGEO DrugPerturbations 2025 (305)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (12)

A gene set library provided by LINCS

rummageo chemical perturbations (164)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
BCKDHA Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Ketoleucine Metabolite (Entity type)
GW-6471 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BCKDHA Gene (Entity type)	-0.008539033
BCKDHA Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Thiamine diphosphate Metabolite (Entity type)
ACDPP Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BCKDHA Gene (Entity type)	-0.020778919
BCKDHA Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	3-Methyl-2-oxovaleric acid Metabolite (Entity type)
BCKDHA Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Ketoisovaleric acid Metabolite (Entity type)
BCKDHA Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	3-Methyl pyruvic acid Metabolite (Entity type)
BCKDHA Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	(S)-3-Methyl-2-oxopentanoic acid Metabolite (Entity type)

BCKDHA
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Ketoleucine
Metabolite (Entity type)

GW-6471
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BCKDHA
Gene (Entity type)
-0.008539033

BCKDHA
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Thiamine diphosphate
Metabolite (Entity type)

ACDPP
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BCKDHA
Gene (Entity type)
-0.020778919

BCKDHA
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
3-Methyl-2-oxovaleric acid
Metabolite (Entity type)

BCKDHA
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Ketoisovaleric acid
Metabolite (Entity type)

BCKDHA
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
3-Methyl pyruvic acid
Metabolite (Entity type)

BCKDHA
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
(S)-3-Methyl-2-oxopentanoic acid
Metabolite (Entity type)

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

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