HBB (Gene)

Entrez Gene ID: 3043

Description: hemoglobin subunit beta

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HBB's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HBB.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HBB.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HBB.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HBB.

Gene Sets (5906)

LINCS L1000 Chem Pert Consensus Sigs (1713)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (2)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (1368)

A gene set library provided by LINCS

rummageo gene perturbations (60)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (53)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (44)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (2606)

A gene set library provided by LINCS

rummageo chemical perturbations (45)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (6)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (4)

A gene set library provided by GTEx

HuBMAP ASCT-B (2)

A gene set library provided by HuBMAP

IDG Drug Targets 2022 (1)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
enevalproate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HBB Gene (Entity type)	0.01393553
Manidipine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HBB Gene (Entity type)	-0.0046476997
Salubrinal Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HBB Gene (Entity type)	-0.0055215517
APEC Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HBB Gene (Entity type)	0.029373636
Ro 40-6055 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HBB Gene (Entity type)	0.0055194115
dichlorodiamine-platinum Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HBB Gene (Entity type)	-0.018380335
Decafluorobutane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HBB Gene (Entity type)	-0.008397236
III606050 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HBB Gene (Entity type)	-0.011995844
Nomilin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HBB Gene (Entity type)	0.012861352
N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-9H-fluorene-2-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HBB Gene (Entity type)	-0.009404932

enevalproate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HBB
Gene (Entity type)
0.01393553

Manidipine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HBB
Gene (Entity type)
-0.0046476997

Salubrinal
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HBB
Gene (Entity type)
-0.0055215517

APEC
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HBB
Gene (Entity type)
0.029373636

Ro 40-6055
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HBB
Gene (Entity type)
0.0055194115

dichlorodiamine-platinum
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HBB
Gene (Entity type)
-0.018380335

Decafluorobutane
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HBB
Gene (Entity type)
-0.008397236

III606050
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HBB
Gene (Entity type)
-0.011995844

Nomilin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HBB
Gene (Entity type)
0.012861352

N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-9H-fluorene-2-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HBB
Gene (Entity type)
-0.009404932

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Knowledge Graph Assertions

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CFDE Workbench

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.