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CFDE Workbench

HBB (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:CD113t-C, ECYT6, ENTREZ:3043, HBB, HGNC:4827, MIM:141900, NM_000518, NP_000509, beta-globin, hemoglobin subunit beta
Omim:OMIM:141900
Nci:C84951
Id:ENSG00000244734
Hgnc:HGNC:4827
Entrez:3043
Ensembl:ENSG00000244734
Description:hemoglobin subunit beta
The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HBB's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HBB.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HBB.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HBB.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HBB.

Results found

Linked to

 

Label

Description

 

Gene Set

T60-Adrenal Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

Phenotype

Ataxia

Phenotype (Entity type)

Cerebellar ataxia refers to ataxia due to dysfunction of the cerebellum. This causes a variety of el...

Gene Set

GSE178340 carfilzomib MM1.S 1 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE178340 1 V 3 CARFILZOMIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE114492 GSE153671 KMT2D inhibition 2 v 11 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE165548 gemcitabine 2 v 13 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE214480 TMIGD2 knockdown HEL-30 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE168401 harmine U2OS 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE210093 TAF15 overexpression A-549 3 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE222758 clofazimine U2OS 0 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    T60-Adrenal Consensus

    Gene Set (Entity type)

    A Gene Set from MoTrPAC

  • Phenotype

    Ataxia

    Phenotype (Entity type)

    Cerebellar ataxia refers to ataxia due to dysfunction of the cerebellum. This causes a variety of el...

  • Gene Set

    GSE178340 carfilzomib MM1.S 1 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE178340 1 V 3 CARFILZOMIB HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE114492 GSE153671 KMT2D inhibition 2 v 11 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE165548 gemcitabine 2 v 13 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE214480 TMIGD2 knockdown HEL-30 1 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE168401 harmine U2OS 1 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE210093 TAF15 overexpression A-549 3 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE222758 clofazimine U2OS 0 v 3 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.