HLA-B (Gene)

Entrez Gene ID: 3106

Description: major histocompatibility complex, class I, B

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HLA-B's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HLA-B.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HLA-B.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HLA-B.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HLA-B.

Gene Sets (3532)

LINCS L1000 Chem Pert Consensus Sigs (771)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (20)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (2)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (567)

A gene set library provided by LINCS

rummageo gene perturbations (265)

A gene set library provided by LINCS

RummaGEO DrugPerturbations 2025 (535)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (911)

A gene set library provided by LINCS

rummageo chemical perturbations (460)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
KBG Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-B Gene (Entity type)	-0.0036007215
Pefloxacin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-B Gene (Entity type)	-0.009191285
AG-99 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-B Gene (Entity type)	-0.009056324
PACOCF3 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-B Gene (Entity type)	-0.005014379
doxorubicin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-B Gene (Entity type)	0.0070283534
2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-B Gene (Entity type)	-0.0039441455
Brequinar Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-B Gene (Entity type)	0.009347127
SA-1472548 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-B Gene (Entity type)	-0.012370985
4-(9-chloro-7-(2,6-difluorophenyl)-5H-benzo[e]pyrimido[5,4-c]azepin-2-ylamino)benzoic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-B Gene (Entity type)	-0.0038069529
SID11113872 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-B Gene (Entity type)	-0.005319176

KBG
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-B
Gene (Entity type)
-0.0036007215

Pefloxacin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-B
Gene (Entity type)
-0.009191285

AG-99
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-B
Gene (Entity type)
-0.009056324

PACOCF3
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-B
Gene (Entity type)
-0.005014379

doxorubicin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-B
Gene (Entity type)
0.0070283534

2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-B
Gene (Entity type)
-0.0039441455

Brequinar
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-B
Gene (Entity type)
0.009347127

SA-1472548
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-B
Gene (Entity type)
-0.012370985

4-(9-chloro-7-(2,6-difluorophenyl)-5H-benzo[e]pyrimido[5,4-c]azepin-2-ylamino)benzoic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-B
Gene (Entity type)
-0.0038069529

SID11113872
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-B
Gene (Entity type)
-0.005319176

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.