HLA-DRA (Gene)

Ensembl Gene ID: ENSG00000204287

Entrez Gene ID: 3122

Description: major histocompatibility complex, class II, DR alpha

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HLA-DRA's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HLA-DRA.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HLA-DRA.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HLA-DRA.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HLA-DRA.

Gene Sets (2109)

LINCS L1000 Chem Pert Consensus Sigs (480)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (6)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (14)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (346)

A gene set library provided by LINCS

rummageo gene perturbations (185)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (270)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (587)

A gene set library provided by LINCS

rummageo chemical perturbations (205)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (2)

A gene set library provided by GTEx

HuBMAP ASCT-B (13)

A gene set library provided by HuBMAP

Knowledge Graph Assertions

Source	Relation	Target	Evidence
4-(4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl)-2-methoxypyrimidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DRA Gene (Entity type)	-0.009585608
(1S,3'R,4'S,5'S,6'R)-6-[(4-Ethylphenyl)methyl]-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-3',4',5'-triol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DRA Gene (Entity type)	0.006800347
Atovaquone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DRA Gene (Entity type)	-0.006143691
benzyl-benzoate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DRA Gene (Entity type)	0.006151945
SID11112839 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DRA Gene (Entity type)	0.0038962632
rel-Mefloquine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DRA Gene (Entity type)	-0.0040568877
indole-3-propionic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DRA Gene (Entity type)	0.0060749175
vincamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DRA Gene (Entity type)	-0.0049723736
salicyl-alcohol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DRA Gene (Entity type)	-0.04284377
CHEMBL3360855::EPZ005687::US9175331, 7 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DRA Gene (Entity type)	0.015442417

4-(4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl)-2-methoxypyrimidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-DRA
Gene (Entity type)
-0.009585608

(1S,3'R,4'S,5'S,6'R)-6-[(4-Ethylphenyl)methyl]-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-3',4',5'-triol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-DRA
Gene (Entity type)
0.006800347

Atovaquone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-DRA
Gene (Entity type)
-0.006143691

benzyl-benzoate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-DRA
Gene (Entity type)
0.006151945

SID11112839
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-DRA
Gene (Entity type)
0.0038962632

rel-Mefloquine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-DRA
Gene (Entity type)
-0.0040568877

indole-3-propionic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-DRA
Gene (Entity type)
0.0060749175

vincamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-DRA
Gene (Entity type)
-0.0049723736

salicyl-alcohol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-DRA
Gene (Entity type)
-0.04284377

CHEMBL3360855::EPZ005687::US9175331, 7
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-DRA
Gene (Entity type)
0.015442417

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.