PEG3 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:5178, HGNC:8826, MIM:601483, NM_001146184, NM_001146185, NM_001146186, NM_001146187, NM_001369717, NM_001369718, NM_001369719, NM_001369720, NM_001369721, NM_001369722, NM_001369723, NM_001369724, NM_001369725, NM_001369726, NM_001369727, NM_001369728, NM_001369729, NM_001369730, NM_001369731, NM_001369732, NM_001369733, NM_001369734, NM_001369735, NM_001369736, NM_001369737, NM_001369738, NM_001369739, NM_006210, NP_001139656, NP_001139657, NP_001139659, NP_001356646, NP_001356647, NP_001356648, NP_001356649, NP_001356650, NP_001356651, NP_001356652, NP_001356653, NP_001356654, NP_001356655, NP_001356656, NP_001356657, NP_001356658, NP_001356659, NP_001356660, NP_001356661, NP_001356662, NP_001356663, NP_001356664, NP_001356665, NP_001356666, NP_001356667, NP_001356668, NP_006201, NR_161475, NR_161476, PEG3, PW1, ZKSCAN22, ZNF904, ZSCAN24, paternally expressed 3

Omim:OMIM:601483

Id:ENSG00000198300

Hgnc:HGNC:8826

Entrez:5178

Ensembl:ENSG00000198300

Description:paternally expressed 3

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2009]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PEG3's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PEG3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PEG3.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PEG3.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PEG3.

Results found

Linked to

	Label	Description
	GSE128255 NDP knockdown stem cell 3 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE48812 sulforaphane 4 v 10 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE261563 CX-5461 5 v 8 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE204836 PP-3 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE151412 sorafenib 2 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE143944 1 V 0 RIBOCICLIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE199862 Chk1 inhibition 0 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE208350 H-7 Huh-7 JHH-7 0 v 8 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE147876 GSE147877 enzalutamide MR42D 2 v 7 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE147876 GSE147877 enzalutamide MR42D 4 v 10 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE128255 NDP knockdown stem cell 3 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE48812 sulforaphane 4 v 10 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE261563 CX-5461 5 v 8 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE204836 PP-3 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE151412 sorafenib 2 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE143944 1 V 0 RIBOCICLIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE199862 Chk1 inhibition 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE208350 H-7 Huh-7 JHH-7 0 v 8 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE147876 GSE147877 enzalutamide MR42D 2 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE147876 GSE147877 enzalutamide MR42D 4 v 10 human dn

Gene Set (Entity type)

A Gene Set from LINCS

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.