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CFDE Workbench

MYO6 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:DFNA22, DFNB37, ENTREZ:4646, HGNC:7605, MIM:600970, MYO6, NM_001300899, NM_001368136, NM_001368137, NM_001368138, NM_001368139, NM_001368140, NM_001368865, NM_001368866, NM_004999, NP_001287828, NP_001355065, NP_001355066, NP_001355067, NP_001355068, NP_001355069, NP_001355794, NP_001355795, NP_004990, NR_160538, NR_160539, XM_005248721, XM_005248722, XM_005248724, XM_017010899, XM_024446447, XP_005248778, XP_005248779, XP_005248781, XP_016866388, XP_024302215, myosin VI
Omim:OMIM:600970
Id:ENSG00000196586
Hgnc:HGNC:7605
Entrez:4646
Ensembl:ENSG00000196586
Description:myosin VI
This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MYO6's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with MYO6.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MYO6.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MYO6.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MYO6.

Results found

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Label

Description

 

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GSE199859 A-7 HCA7 1 v 2 human up

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GSE228619 cadherin-11 CDH11 knockdown RNA Small Interfering 0 v 1 human dn

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GSE110709 GSK-J4 5 v 3 human dn

Gene Set (Entity type)

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GSE213588 trametinib NF1 8 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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GSE164874 prednisolone muscle organ 5 v 9 human up

Gene Set (Entity type)

A Gene Set from LINCS

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GSE118548 1 V 2 TRAMETINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

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GSE214306 CCM1 knockout 4 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

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GSE156648 DOT1L overexpression IMR-90 2 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE118548 trametinib T84 1 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE252944 AKT inhibition 7 v 9 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE199859 A-7 HCA7 1 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE228619 cadherin-11 CDH11 knockdown RNA Small Interfering 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE110709 GSK-J4 5 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE213588 trametinib NF1 8 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE164874 prednisolone muscle organ 5 v 9 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE118548 1 V 2 TRAMETINIB HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE214306 CCM1 knockout 4 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE156648 DOT1L overexpression IMR-90 2 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
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