H1-0 (Gene)

Entrez Gene ID: 3005

Description: H1.0 linker histone

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View H1-0's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with H1-0.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using H1-0.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for H1-0.

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Gene Sets (2514)

rummageo gene perturbations (306)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1712)

A gene set library provided by LINCS

rummageo chemical perturbations (496)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-(5-Methoxy-1H-indol-3-yl)-ethylamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-0 Gene (Entity type)	-0.011004197
Tilmicosin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-0 Gene (Entity type)	-0.04180705
N-(6-methylbenzo[d]thiazol-2-yl)-2-(4-oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-ylthio)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	H1-0 Gene (Entity type)	0.0093470225
Safinamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-0 Gene (Entity type)	-0.004316018
5-{2-[2-(2-Ethoxy-phenoxy)-ethylamino]-propyl}-2-methoxy-benzenesulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-0 Gene (Entity type)	-0.004859774
SID11112216 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-0 Gene (Entity type)	-0.021063933
MDM2-inhibitor Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-0 Gene (Entity type)	-0.010181042
diazepam Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-0 Gene (Entity type)	-0.003354781
orthothymotinic-acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	H1-0 Gene (Entity type)	0.015965754
lacosamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-0 Gene (Entity type)	-0.005296117

2-(5-Methoxy-1H-indol-3-yl)-ethylamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-0
Gene (Entity type)
-0.011004197

Tilmicosin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-0
Gene (Entity type)
-0.04180705

N-(6-methylbenzo[d]thiazol-2-yl)-2-(4-oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-ylthio)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
H1-0
Gene (Entity type)
0.0093470225

Safinamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-0
Gene (Entity type)
-0.004316018

5-{2-[2-(2-Ethoxy-phenoxy)-ethylamino]-propyl}-2-methoxy-benzenesulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-0
Gene (Entity type)
-0.004859774

SID11112216
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-0
Gene (Entity type)
-0.021063933

MDM2-inhibitor
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-0
Gene (Entity type)
-0.010181042

diazepam
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-0
Gene (Entity type)
-0.003354781

orthothymotinic-acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
H1-0
Gene (Entity type)
0.015965754

lacosamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-0
Gene (Entity type)
-0.005296117

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.