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PRAME (Gene)

Ensembl Gene ID: ENSG00000185686

Entrez Gene ID: 23532

Description: PRAME nuclear receptor transcriptional regulator

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PRAME's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PRAME.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PRAME.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PRAME.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

This repository is under review for potential modification in compliance with Administration directives.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	ML-133 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRAME Gene (Entity type)	0.005314805
	L-745870 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRAME Gene (Entity type)	-0.0076629193
	vanillyl-glycol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRAME Gene (Entity type)	0.012877517
	Methysergide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRAME Gene (Entity type)	-0.0062429104
	3-(2-cyano-3-(trifluoromethyl)phenoxy)phenyl 4,4,4-trifluorobutane-1-sulfonate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRAME Gene (Entity type)	-0.00792104
	Tazobactam Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRAME Gene (Entity type)	0.005103757
	N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRAME Gene (Entity type)	-0.01365848
	MW-STK33-2B Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRAME Gene (Entity type)	0.015394794
	immethridine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRAME Gene (Entity type)	-0.00936683
	L-690330 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRAME Gene (Entity type)	-0.0032022095

ML-133
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRAME
Gene (Entity type)
0.005314805

L-745870
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRAME
Gene (Entity type)
-0.0076629193

vanillyl-glycol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRAME
Gene (Entity type)
0.012877517

Methysergide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRAME
Gene (Entity type)
-0.0062429104

3-(2-cyano-3-(trifluoromethyl)phenoxy)phenyl 4,4,4-trifluorobutane-1-sulfonate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRAME
Gene (Entity type)
-0.00792104

Tazobactam
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRAME
Gene (Entity type)
0.005103757

N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRAME
Gene (Entity type)
-0.01365848

MW-STK33-2B
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRAME
Gene (Entity type)
0.015394794

immethridine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRAME
Gene (Entity type)
-0.00936683

L-690330
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRAME
Gene (Entity type)
-0.0032022095

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