DLK1 (Gene)

Entrez Gene ID: 8788

Description: delta like non-canonical Notch ligand 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View DLK1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with DLK1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using DLK1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for DLK1.

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Gene Sets (7799)

LINCS L1000 Chem Pert Consensus Sigs (2171)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (2)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (5)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (2073)

A gene set library provided by LINCS

rummageo gene perturbations (63)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (17)

A gene set library provided by GTEx

LINCS L1000 Consensus Median Signatures (3372)

A gene set library provided by LINCS

rummageo chemical perturbations (80)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (13)

A gene set library provided by GTEx

IDG Drug Targets 2022 (1)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DLK1 Gene (Entity type)	-0.004312275
nifuroxazide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DLK1 Gene (Entity type)	-0.023980105
PSH-003 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DLK1 Gene (Entity type)	0.012089224
RAN-27 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DLK1 Gene (Entity type)	0.009477249
Myriocin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DLK1 Gene (Entity type)	0.005410333
MW-SHH-28 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DLK1 Gene (Entity type)	-0.0036151872
2-(5-Methoxy-1H-indol-3-yl)-ethylamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DLK1 Gene (Entity type)	-0.008362946
(E)-N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DLK1 Gene (Entity type)	0.004116707
glutamyldopamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DLK1 Gene (Entity type)	-0.014049034
N-(2-aminophenyl)-4-(((((2R,3S)-9-(dimethylamino)-5-((R)-1-hydroxypropan-2-yl)-3-methyl-6-oxo-2,3,4,5,6,7-hexahydrobenzo[h][1,5]oxazonin-2-yl)methyl)(methyl)amino)methyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DLK1 Gene (Entity type)	-0.009603214

N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DLK1
Gene (Entity type)
-0.004312275

nifuroxazide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DLK1
Gene (Entity type)
-0.023980105

PSH-003
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DLK1
Gene (Entity type)
0.012089224

RAN-27
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DLK1
Gene (Entity type)
0.009477249

Myriocin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DLK1
Gene (Entity type)
0.005410333

MW-SHH-28
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DLK1
Gene (Entity type)
-0.0036151872

2-(5-Methoxy-1H-indol-3-yl)-ethylamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DLK1
Gene (Entity type)
-0.008362946

(E)-N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DLK1
Gene (Entity type)
0.004116707

glutamyldopamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DLK1
Gene (Entity type)
-0.014049034

N-(2-aminophenyl)-4-(((((2R,3S)-9-(dimethylamino)-5-((R)-1-hydroxypropan-2-yl)-3-methyl-6-oxo-2,3,4,5,6,7-hexahydrobenzo[h][1,5]oxazonin-2-yl)methyl)(methyl)amino)methyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DLK1
Gene (Entity type)
-0.009603214

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.