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ADO (Gene)

Ensembl Gene ID: ENSG00000181915

Entrez Gene ID: 84890

Description: 2-aminoethanethiol dioxygenase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ADO's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ADO.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ADO.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ADO.

Gene Sets (3507)

LINCS L1000 Chem Pert Consensus Sigs (939)

A gene set library provided by LINCS

Illuminating the Druggable Genome

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (1155)

A gene set library provided by LINCS

rummageo gene perturbations (113)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1147)

A gene set library provided by LINCS

rummageo chemical perturbations (151)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Tetrahydrobiopterin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADO Gene (Entity type)	-0.008263035
	SID11113872 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADO Gene (Entity type)	0.0059183897
	Succinylsulfathiazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADO Gene (Entity type)	-0.015750187
	EMF-csc-9 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADO Gene (Entity type)	0.0060791266
	N-(3-(5-iodo-4-(3-(thiophene-2-carboxamido)propylamino)pyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADO Gene (Entity type)	0.0072511607
	9,10,11,12,tetrahydro-9,12-epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-1,3(2H)-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADO Gene (Entity type)	0.01296747
	SA-1920453 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADO Gene (Entity type)	0.010292182
	SID11114229 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADO Gene (Entity type)	-0.002977853
	2,3,7,8-Tetrachlorodibenzo-P-Dioxin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADO Gene (Entity type)	0.0096908985
	cinobufagin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADO Gene (Entity type)	-0.014709314

Tetrahydrobiopterin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADO
Gene (Entity type)
-0.008263035

SID11113872
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADO
Gene (Entity type)
0.0059183897

Succinylsulfathiazole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADO
Gene (Entity type)
-0.015750187

EMF-csc-9
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADO
Gene (Entity type)
0.0060791266

N-(3-(5-iodo-4-(3-(thiophene-2-carboxamido)propylamino)pyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADO
Gene (Entity type)
0.0072511607

9,10,11,12,tetrahydro-9,12-epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-1,3(2H)-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADO
Gene (Entity type)
0.01296747

SA-1920453
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADO
Gene (Entity type)
0.010292182

SID11114229
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADO
Gene (Entity type)
-0.002977853

2,3,7,8-Tetrachlorodibenzo-P-Dioxin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADO
Gene (Entity type)
0.0096908985

cinobufagin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADO
Gene (Entity type)
-0.014709314

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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