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AURKB (Gene)

Ensembl Gene ID: ENSG00000178999

Entrez Gene ID: 9212

Description: aurora kinase B

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View AURKB's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with AURKB.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using AURKB.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for AURKB.

Gene Sets (3721)

LINCS L1000 Chem Pert Consensus Sigs (493)

A gene set library provided by LINCS

Illuminating the Druggable Genome

ARCHS4 IDG Coexp (13)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (737)

A gene set library provided by LINCS

rummageo gene perturbations (193)

A gene set library provided by LINCS

Genotype Tissue Expression

GTEx Aging Signatures 2021 (11)

A gene set library provided by GTEx

LINCS L1000 Consensus Median Signatures (1914)

A gene set library provided by LINCS

rummageo chemical perturbations (344)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

Genotype Tissue Expression

GTEx Tissues V8 2023 (2)

A gene set library provided by GTEx

Illuminating the Druggable Genome

IDG Drug Targets 2022 (11)

A gene set library provided by IDG

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Quinoclamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AURKB Gene (Entity type)	-0.0077587334
	AM251 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AURKB Gene (Entity type)	-0.003939682
	9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AURKB Gene (Entity type)	0.010340531
	SID11111390 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AURKB Gene (Entity type)	-0.015222791
	HLI-373 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AURKB Gene (Entity type)	-0.007252201
	tirasemtiv Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AURKB Gene (Entity type)	0.0058160736
	1-(3-((((2R,3S,4R,5R)-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-tert-butylphenyl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AURKB Gene (Entity type)	0.0105726505
	SID103905684 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AURKB Gene (Entity type)	-0.003700781
	SID11113667 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AURKB Gene (Entity type)	0.0069656004
	EBPC Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AURKB Gene (Entity type)	0.005913651

Quinoclamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AURKB
Gene (Entity type)
-0.0077587334

AM251
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AURKB
Gene (Entity type)
-0.003939682

9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AURKB
Gene (Entity type)
0.010340531

SID11111390
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AURKB
Gene (Entity type)
-0.015222791

HLI-373
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AURKB
Gene (Entity type)
-0.007252201

tirasemtiv
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AURKB
Gene (Entity type)
0.0058160736

1-(3-((((2R,3S,4R,5R)-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-tert-butylphenyl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AURKB
Gene (Entity type)
0.0105726505

SID103905684
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AURKB
Gene (Entity type)
-0.003700781

SID11113667
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AURKB
Gene (Entity type)
0.0069656004

EBPC
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AURKB
Gene (Entity type)
0.005913651

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.