SEZ6L2 (Gene)

Entrez Gene ID: 26470

Description: seizure related 6 homolog like 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SEZ6L2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with SEZ6L2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SEZ6L2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SEZ6L2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SEZ6L2.

Gene Sets (2219)

LINCS L1000 Chem Pert Consensus Sigs (403)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (28)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (14)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (315)

A gene set library provided by LINCS

rummageo gene perturbations (213)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (6)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (384)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (521)

A gene set library provided by LINCS

rummageo chemical perturbations (332)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
VU-0424206-1 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SEZ6L2 Gene (Entity type)	0.012523298
8-chloro-4-(3-chloro-4-fluorophenylamino)-6-((1-(1-ethylpiperidin-4-yl)-1H-1,2,3-triazol-4-yl)methylamino)quinoline-3-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SEZ6L2 Gene (Entity type)	-0.003401502
SID11113868 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SEZ6L2 Gene (Entity type)	-0.0072029736
FPL-55712 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SEZ6L2 Gene (Entity type)	-0.0031571498
(-)-Epicatechin Gallate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SEZ6L2 Gene (Entity type)	0.008360082
ST-013960 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SEZ6L2 Gene (Entity type)	-0.0085717365
chlordiazepoxide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SEZ6L2 Gene (Entity type)	0.012758532
triacetylresveratrol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SEZ6L2 Gene (Entity type)	0.01673216
17-methyl-testosterone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SEZ6L2 Gene (Entity type)	-0.0030835203

VU-0424206-1
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SEZ6L2
Gene (Entity type)
0.012523298

8-chloro-4-(3-chloro-4-fluorophenylamino)-6-((1-(1-ethylpiperidin-4-yl)-1H-1,2,3-triazol-4-yl)methylamino)quinoline-3-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SEZ6L2
Gene (Entity type)
-0.003401502

SID11113868
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SEZ6L2
Gene (Entity type)
-0.0072029736

FPL-55712
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SEZ6L2
Gene (Entity type)
-0.0031571498

(-)-Epicatechin Gallate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SEZ6L2
Gene (Entity type)
0.008360082

ST-013960
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SEZ6L2
Gene (Entity type)
-0.0085717365

chlordiazepoxide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SEZ6L2
Gene (Entity type)
0.012758532

triacetylresveratrol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SEZ6L2
Gene (Entity type)
0.01673216

17-methyl-testosterone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SEZ6L2
Gene (Entity type)
-0.0030835203

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Knowledge Graph Assertions

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

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