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PIK3CD (Gene)

Ensembl Gene ID: ENSG00000171608

Entrez Gene ID: 5293

Description: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PIK3CD's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PIK3CD.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PIK3CD.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PIK3CD.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

This repository is under review for potential modification in compliance with Administration directives.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	PIK3CD Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ATP Metabolite (Entity type)
	KFGENEBIN:PIK3CD-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	PIK3CD Gene (Entity type)
	PIK3CD Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	atp binding Metabolite (Entity type)
	PIK3CD Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ADP Metabolite (Entity type)
	Inosine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PIK3CD Gene (Entity type)	0.0050809006
	tramiprosate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PIK3CD Gene (Entity type)	-0.0038137548
	N-(3-Fluorophenyl)-1-[(4-([(3S)-3-methyl-1-piperazinyl]methyl)phenyl)acetyl]-4-piperidinamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PIK3CD Gene (Entity type)	-0.005525956
	SA-1939938 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PIK3CD Gene (Entity type)	-0.012860446
	1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PIK3CD Gene (Entity type)	0.0039449814
	PIK3CD Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Adenosine Diphosphate Metabolite (Entity type)

PIK3CD
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
ATP
Metabolite (Entity type)

KFGENEBIN:PIK3CD-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
PIK3CD
Gene (Entity type)

PIK3CD
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
atp binding
Metabolite (Entity type)

PIK3CD
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
ADP
Metabolite (Entity type)

Inosine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PIK3CD
Gene (Entity type)
0.0050809006

tramiprosate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PIK3CD
Gene (Entity type)
-0.0038137548

N-(3-Fluorophenyl)-1-[(4-([(3S)-3-methyl-1-piperazinyl]methyl)phenyl)acetyl]-4-piperidinamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PIK3CD
Gene (Entity type)
-0.005525956

SA-1939938
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PIK3CD
Gene (Entity type)
-0.012860446

1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carboxylic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PIK3CD
Gene (Entity type)
0.0039449814

PIK3CD
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Adenosine Diphosphate
Metabolite (Entity type)

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