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CST1 (Gene)

Ensembl Gene ID: ENSG00000170373

Entrez Gene ID: 1469

Description: cystatin SN

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CST1's neighborhood in the knowledge graph.

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CST1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CST1.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CST1.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CST1.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

This repository is under review for potential modification in compliance with Administration directives.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	cortisone-acetate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CST1 Gene (Entity type)	0.006075012
	1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CST1 Gene (Entity type)	-0.0074755163
	6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CST1 Gene (Entity type)	0.018514711
	azacyclonol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CST1 Gene (Entity type)	-0.0081067
	8-chloro-4-(3-chloro-4-fluorophenylamino)-6-((1-(1-ethylpiperidin-4-yl)-1H-1,2,3-triazol-4-yl)methylamino)quinoline-3-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CST1 Gene (Entity type)	-0.0035038255
	LY-278584 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CST1 Gene (Entity type)	-0.008404793
	ethyl 6-(4-(benzylsulfonylcarbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CST1 Gene (Entity type)	-0.022633241
	1-(1-(3-(Methylsulfonyl)-phenyl)-7-propoxyindolizin-3-yl)ethanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CST1 Gene (Entity type)	-0.021660043
	Epidepride Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CST1 Gene (Entity type)	-0.017071582
	EBIO Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CST1 Gene (Entity type)	-0.03623483

cortisone-acetate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CST1
Gene (Entity type)
0.006075012

1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CST1
Gene (Entity type)
-0.0074755163

6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CST1
Gene (Entity type)
0.018514711

azacyclonol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CST1
Gene (Entity type)
-0.0081067

8-chloro-4-(3-chloro-4-fluorophenylamino)-6-((1-(1-ethylpiperidin-4-yl)-1H-1,2,3-triazol-4-yl)methylamino)quinoline-3-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CST1
Gene (Entity type)
-0.0035038255

LY-278584
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CST1
Gene (Entity type)
-0.008404793

ethyl 6-(4-(benzylsulfonylcarbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CST1
Gene (Entity type)
-0.022633241

1-(1-(3-(Methylsulfonyl)-phenyl)-7-propoxyindolizin-3-yl)ethanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CST1
Gene (Entity type)
-0.021660043

Epidepride
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CST1
Gene (Entity type)
-0.017071582

EBIO
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CST1
Gene (Entity type)
-0.03623483

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