EMX2 (Gene)

Organism:

Homo sapiens

Synonyms:EMX2, ENTREZ:2018, HGNC:3341, MIM:600035, NM_001165924, NM_004098, NP_001159396, NP_004089, empty spiracles homeobox 2

Omim:OMIM:600035

Id:ENSG00000170370

Hgnc:HGNC:3341

Entrez:2018

Ensembl:ENSG00000170370

Description:empty spiracles homeobox 2

This gene encodes a homeobox-containing transcription factor that is the homolog to the 'empty spiracles' gene in Drosophila. Research on this gene in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenetial system. It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing results in multiple transcript variants encoding distinct proteins.[provided by RefSeq, Sep 2009]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View EMX2's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with EMX2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using EMX2.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for EMX2.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with EMX2.

Results found

Linked to

	Label	Description
	GSE117805 A-66 3 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE117805 A-66 0 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE232435 TAK1 inhibition 0 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE227891 2 V 0 ETHANOL MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE93124 crizotinib SW480 0 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE157594 0 V 7 NICOTINAMIDE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE125782 0 V 1 GLUTAMINE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE128844 chloroquine 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE155852 0 V 2 APIGENIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE101239 4 V 1 VALPROIC ACID MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS

GSE117805 A-66 3 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE117805 A-66 0 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE232435 TAK1 inhibition 0 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE227891 2 V 0 ETHANOL MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE93124 crizotinib SW480 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE157594 0 V 7 NICOTINAMIDE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE125782 0 V 1 GLUTAMINE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE128844 chloroquine 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE155852 0 V 2 APIGENIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE101239 4 V 1 VALPROIC ACID MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.