KLK11 (Gene)

Entrez Gene ID: 11012

Description: kallikrein related peptidase 11

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View KLK11's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with KLK11.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using KLK11.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for KLK11.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with KLK11.

Gene Sets (4426)

LINCS L1000 Chem Pert Consensus Sigs (1211)

A gene set library provided by LINCS

GlyGen Glycosylated Proteins 2022 (1)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (8)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1303)

A gene set library provided by LINCS

rummageo gene perturbations (29)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (11)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (58)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1752)

A gene set library provided by LINCS

rummageo chemical perturbations (49)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (3)

A gene set library provided by GTEx

HuBMAP ASCT-B (1)

A gene set library provided by HuBMAP

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Estriol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KLK11 Gene (Entity type)	0.0033224446
SA-84869 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KLK11 Gene (Entity type)	0.01556934
butabindide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KLK11 Gene (Entity type)	-0.009349381
SA-103150 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KLK11 Gene (Entity type)	0.014560796
TG-100801 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KLK11 Gene (Entity type)	0.003921359
YL-52 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KLK11 Gene (Entity type)	0.013889941
DAC-013 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KLK11 Gene (Entity type)	0.01131078
lupanine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KLK11 Gene (Entity type)	-0.0036624805
nifekalant Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KLK11 Gene (Entity type)	0.010877405
fingolimod Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KLK11 Gene (Entity type)	0.0049657803

Estriol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KLK11
Gene (Entity type)
0.0033224446

SA-84869
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KLK11
Gene (Entity type)
0.01556934

butabindide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KLK11
Gene (Entity type)
-0.009349381

SA-103150
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KLK11
Gene (Entity type)
0.014560796

TG-100801
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KLK11
Gene (Entity type)
0.003921359

YL-52
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KLK11
Gene (Entity type)
0.013889941

DAC-013
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KLK11
Gene (Entity type)
0.01131078

lupanine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KLK11
Gene (Entity type)
-0.0036624805

nifekalant
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KLK11
Gene (Entity type)
0.010877405

fingolimod
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KLK11
Gene (Entity type)
0.0049657803

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.