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CYB5R2 (Gene)

Ensembl Gene ID: ENSG00000166394

Entrez Gene ID: 51700

Description: cytochrome b5 reductase 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CYB5R2's neighborhood in the knowledge graph.

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CYB5R2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CYB5R2.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CYB5R2.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CYB5R2.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

This repository is under review for potential modification in compliance with Administration directives.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	E4031 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYB5R2 Gene (Entity type)	0.003488934
	albendazole-oxide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYB5R2 Gene (Entity type)	0.04740492
	ranitidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYB5R2 Gene (Entity type)	-0.0031132551
	Citiolone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYB5R2 Gene (Entity type)	-0.022388887
	benzatropine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYB5R2 Gene (Entity type)	-0.010349299
	zamifenacin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYB5R2 Gene (Entity type)	-0.006765733
	tinidazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYB5R2 Gene (Entity type)	0.008952217
	ceforanide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYB5R2 Gene (Entity type)	-0.0077042473
	6-[(3S,4S)-4-Methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYB5R2 Gene (Entity type)	0.0034834843
	Brexpiprazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYB5R2 Gene (Entity type)	-0.0037516828

E4031
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CYB5R2
Gene (Entity type)
0.003488934

albendazole-oxide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CYB5R2
Gene (Entity type)
0.04740492

ranitidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CYB5R2
Gene (Entity type)
-0.0031132551

Citiolone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CYB5R2
Gene (Entity type)
-0.022388887

benzatropine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CYB5R2
Gene (Entity type)
-0.010349299

zamifenacin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CYB5R2
Gene (Entity type)
-0.006765733

tinidazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CYB5R2
Gene (Entity type)
0.008952217

ceforanide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CYB5R2
Gene (Entity type)
-0.0077042473

6-[(3S,4S)-4-Methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CYB5R2
Gene (Entity type)
0.0034834843

Brexpiprazole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CYB5R2
Gene (Entity type)
-0.0037516828

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