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CFDE Workbench

CYB5R2 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:B5R.2, CYB5R2, ENTREZ:51700, HGNC:24376, MIM:608342, NM_001001336, NM_001302826, NM_001302827, NM_016229, NP_001289755, NP_001289756, NP_057313, NR_126508, XM_005252975, XM_006718251, XM_011520184, XM_011520185, XM_017017920, XM_017017921, XM_017017922, XM_024448580, XM_024448581, XM_024448582, XP_005253032, XP_006718314, XP_011518486, XP_011518487, XP_016873409, XP_016873410, XP_016873411, XP_024304348, XP_024304349, XP_024304350, XR_002957151, cytochrome b5 reductase 2
Omim:OMIM:608342
Id:ENSG00000166394
Hgnc:HGNC:24376
Entrez:51700
Ensembl:ENSG00000166394
Description:cytochrome b5 reductase 2
The protein encoded by this gene belongs to the flavoprotein pyridine nucleotide cytochrome reductase family of proteins. Cytochrome b-type NAD(P)H oxidoreductases are implicated in many processes including cholesterol biosynthesis, fatty acid desaturation and elongation, and respiratory burst in neutrophils and macrophages. Cytochrome b5 reductases have soluble and membrane-bound forms that are the product of alternative splicing. In animal cells, the membrane-bound form binds to the endoplasmic reticulum, where it is a member of a fatty acid desaturation complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

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Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CYB5R2's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CYB5R2.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CYB5R2.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CYB5R2.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CYB5R2.

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    A Gene Set from LINCS

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    GSE252944 AKT inhibition 7 v 9 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    GSE239844 crizotinib 11 v 9 human dn

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    A Gene Set from LINCS

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    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

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    A Gene Set from LINCS

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    GSE213588 trametinib NF1 9 v 5 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE202434 GSE202438 talazoparib 8 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE202434 GSE202438 talazoparib 13 v 5 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE202434 GSE202438 talazoparib 9 v 5 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE213588 8 V 0 TRAMETINIB HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
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