APBB2 (Gene)

Organism:

Homo sapiens

Synonyms:APBB2, ENTREZ:323, FE65L, FE65L1, HGNC:582, MIM:602710, NM_001166050, NM_001166051, NM_001166052, NM_001166053, NM_001166054, NM_001330656, NM_001330658, NM_004307, NM_173075, NP_001159522, NP_001159523, NP_001159524, NP_001159525, NP_001159526, NP_001317585, NP_001317587, NP_004298, NP_775098, XM_006714005, XM_006714007, XM_006714008, XM_006714009, XM_006714010, XM_006714011, XM_006714012, XM_011513686, XM_011513687, XM_011513688, XM_017008143, XM_017008144, XM_017008145, XM_017008146, XM_017008147, XM_017008148, XM_017008149, XM_017008151, XM_017008152, XM_017008154, XM_017008156, XM_017008157, XM_017008158, XP_006714068, XP_006714070, XP_006714071, XP_006714072, XP_006714073, XP_006714074, XP_006714075, XP_011511988, XP_011511989, XP_011511990, XP_016863632, XP_016863633, XP_016863634, XP_016863635, XP_016863636, XP_016863637, XP_016863638, XP_016863640, XP_016863641, XP_016863643, XP_016863645, XP_016863646, XP_016863647, amyloid beta precursor protein binding family B member 2

Omim:OMIM:602710

Id:ENSG00000163697

Hgnc:HGNC:582

Entrez:323

Ensembl:ENSG00000163697

Description:amyloid beta precursor protein binding family B member 2

The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View APBB2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with APBB2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using APBB2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for APBB2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with APBB2.

Results found

Linked to

	Label	Description
	GSE179112 GSE179113 hydroxyl Hutt45 4 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE89154 proscillaridin 1 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE120612 etoposide leukocyte 7 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE118548 trametinib T84 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE218097 SOX10 overexpression glial cell 2 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE115542 digoxin 5 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE179667 NVP-BEZ235 U-87MG Uppsala 0 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE115384 CELSR2 knockdown 2 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE89154 1 V 3 PROSCILLARIDIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	Ataxia Phenotype (Entity type)	Cerebellar ataxia refers to ataxia due to dysfunction of the cerebellum. This causes a variety of el...

GSE179112 GSE179113 hydroxyl Hutt45 4 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE89154 proscillaridin 1 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE120612 etoposide leukocyte 7 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE118548 trametinib T84 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE218097 SOX10 overexpression glial cell 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE115542 digoxin 5 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE179667 NVP-BEZ235 U-87MG Uppsala 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE115384 CELSR2 knockdown 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE89154 1 V 3 PROSCILLARIDIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Ataxia

Phenotype (Entity type)

Cerebellar ataxia refers to ataxia due to dysfunction of the cerebellum. This causes a variety of el...

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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