CFDE Workbench
InfoDataCloudKnowledgetrainingcoordination
Search
Graph
Enrichment
Cross
Assistant
Data Matrix
Use Cases
Tools & Workflows
Submit
Documentation
CFDE Workbench

REL (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:C-Rel, ENTREZ:5966, HGNC:9954, HIVEN86A, MIM:164910, NM_001291746, NM_002908, NP_001278675, NP_002899, REL proto-oncogene, NF-kB subunit, REL, XM_011533010, XM_017004627, XP_011531312, XP_016860116
Omim:OMIM:164910
Id:ENSG00000162924
Hgnc:HGNC:9954
Entrez:5966
Ensembl:ENSG00000162924
Description:REL proto-oncogene, NF-kB subunit
This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View REL's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with REL.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using REL.

Submit
Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for REL.

Submit
Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with REL.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE161800 cisplatin A-549 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE235390 4 V 0 LURBINECTEDIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE128730 neratinib OVCAR-8 7 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE235066 carboplatin 4 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE213588 trametinib NF1 10 v 6 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE214505 AKR1B1 knockdown A-549 3 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE202434 GSE202438 talazoparib 13 v 11 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE151090 verteporfin 5 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE191005 ENL knockout MOLM-13 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE213845 EZH2 inhibition 2 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE161800 cisplatin A-549 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE235390 4 V 0 LURBINECTEDIN HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE128730 neratinib OVCAR-8 7 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE235066 carboplatin 4 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE213588 trametinib NF1 10 v 6 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE214505 AKR1B1 knockdown A-549 3 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE202434 GSE202438 talazoparib 13 v 11 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE151090 verteporfin 5 v 4 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE191005 ENL knockout MOLM-13 1 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE213845 EZH2 inhibition 2 v 5 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

    • DISPLAY PER PAGE
    CFDE Workbench
    Report a bug
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    @CFDE Workbench 2026
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.