SIDT2 (Gene)

Entrez Gene ID: 51092

Description: SID1 transmembrane family member 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SIDT2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with SIDT2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SIDT2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SIDT2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SIDT2.

Gene Sets (2511)

LINCS L1000 Chem Pert Consensus Sigs (559)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (10)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (658)

A gene set library provided by LINCS

rummageo gene perturbations (144)

A gene set library provided by LINCS

RummaGEO DrugPerturbations 2025 (325)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (588)

A gene set library provided by LINCS

rummageo chemical perturbations (221)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydro-naphthalen-1-yl]-methanesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SIDT2 Gene (Entity type)	0.04054478
Isoetharine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SIDT2 Gene (Entity type)	0.04420244
LY 165,163 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SIDT2 Gene (Entity type)	0.0070081046
ICI-162846 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SIDT2 Gene (Entity type)	-0.005115509
SID11113789 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SIDT2 Gene (Entity type)	0.03465389
SA-424828 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SIDT2 Gene (Entity type)	0.008130972
2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (Yohimbine) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SIDT2 Gene (Entity type)	-0.003456549
TUL_XIX003 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SIDT2 Gene (Entity type)	-0.0133965975
zaldaride Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SIDT2 Gene (Entity type)	-0.003297222
BG-STK33-03 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SIDT2 Gene (Entity type)	-0.019300526

N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydro-naphthalen-1-yl]-methanesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SIDT2
Gene (Entity type)
0.04054478

Isoetharine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SIDT2
Gene (Entity type)
0.04420244

LY 165,163
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SIDT2
Gene (Entity type)
0.0070081046

ICI-162846
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SIDT2
Gene (Entity type)
-0.005115509

SID11113789
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SIDT2
Gene (Entity type)
0.03465389

SA-424828
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SIDT2
Gene (Entity type)
0.008130972

2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (Yohimbine)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SIDT2
Gene (Entity type)
-0.003456549

TUL_XIX003
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SIDT2
Gene (Entity type)
-0.0133965975

zaldaride
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SIDT2
Gene (Entity type)
-0.003297222

BG-STK33-03
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SIDT2
Gene (Entity type)
-0.019300526

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.