AGTR1 (Gene)

Organism:

Homo sapiens

Synonyms:AG2S, AGTR1, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ENTREZ:185, HAT1R, HGNC:336, MIM:106165, NM_000685, NM_001382736, NM_001382737, NM_004835, NM_009585, NM_031850, NM_032049, NP_000676, NP_001369665, NP_001369666, NP_004826, NP_033611, NP_114038, NP_114438, angiotensin II receptor type 1

Omim:OMIM:106165

Nci:C179872

Id:ENSG00000144891

Hgnc:HGNC:336

Entrez:185

Ensembl:ENSG00000144891

Description:angiotensin II receptor type 1

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2020]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View AGTR1's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with AGTR1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using AGTR1.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for AGTR1.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with AGTR1.

Results found

Linked to

	Label	Description
	T60-Adrenal Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE233647 docetaxel UFERSA-PC3 DU145 4 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE184892 trehalose fibroblast 4 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE202434 GSE202438 talazoparib 4 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE233647 4 V 0 DOCETAXEL HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE108464 AZ-628 1 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE202434 GSE202438 talazoparib 6 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE128844 chloroquine 0 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE184892 4 V 2 TREHALOSE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE151412 sorafenib 2 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS

T60-Adrenal Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE233647 docetaxel UFERSA-PC3 DU145 4 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE184892 trehalose fibroblast 4 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE202434 GSE202438 talazoparib 4 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE233647 4 V 0 DOCETAXEL HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE108464 AZ-628 1 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE202434 GSE202438 talazoparib 6 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE128844 chloroquine 0 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE184892 4 V 2 TREHALOSE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE151412 sorafenib 2 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.