EPHX1 (Gene)

Entrez Gene ID: 2052

Description: epoxide hydrolase 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View EPHX1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with EPHX1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using EPHX1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for EPHX1.

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Gene Sets (3890)

LINCS L1000 Chem Pert Consensus Sigs (1130)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (7)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (6)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (743)

A gene set library provided by LINCS

rummageo gene perturbations (201)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1454)

A gene set library provided by LINCS

rummageo chemical perturbations (336)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (11)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
minodronic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPHX1 Gene (Entity type)	-0.004376854
Siguazodan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPHX1 Gene (Entity type)	-0.0027506328
ALW-II-38-3 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPHX1 Gene (Entity type)	-0.0051550763
Losmapimod Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EPHX1 Gene (Entity type)	0.0049388874
SA-1938219 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPHX1 Gene (Entity type)	-0.015909446
UGISS-451 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EPHX1 Gene (Entity type)	0.010540518
KU-C104133 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPHX1 Gene (Entity type)	-0.014691958
PD-123319 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPHX1 Gene (Entity type)	-0.0036229189
pinitol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EPHX1 Gene (Entity type)	0.0033603278
PSH-028 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EPHX1 Gene (Entity type)	0.012095653

minodronic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPHX1
Gene (Entity type)
-0.004376854

Siguazodan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPHX1
Gene (Entity type)
-0.0027506328

ALW-II-38-3
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPHX1
Gene (Entity type)
-0.0051550763

Losmapimod
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EPHX1
Gene (Entity type)
0.0049388874

SA-1938219
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPHX1
Gene (Entity type)
-0.015909446

UGISS-451
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EPHX1
Gene (Entity type)
0.010540518

KU-C104133
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPHX1
Gene (Entity type)
-0.014691958

PD-123319
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPHX1
Gene (Entity type)
-0.0036229189

pinitol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EPHX1
Gene (Entity type)
0.0033603278

PSH-028
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EPHX1
Gene (Entity type)
0.012095653

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.