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FLG (Gene)

Ensembl Gene ID: ENSG00000143631

Entrez Gene ID: 2312

Description: filaggrin

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View FLG's neighborhood in the knowledge graph.

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with FLG.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using FLG.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for FLG.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with FLG.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

This repository is under review for potential modification in compliance with Administration directives.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	SA-1456570 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FLG Gene (Entity type)	-0.009724473
	colforsin-daproate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FLG Gene (Entity type)	-0.007626442
	SID11113856 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FLG Gene (Entity type)	0.009190929
	fentiazac Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FLG Gene (Entity type)	-0.004246076
	7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FLG Gene (Entity type)	-0.0047177384
	2-morpholino-6-(thianthren-1-yl)-4H-pyran-4-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FLG Gene (Entity type)	-0.0035140328
	N20C Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FLG Gene (Entity type)	-0.005854041
	methyl-dopate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FLG Gene (Entity type)	0.017130766
	Ro 40-6055 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FLG Gene (Entity type)	-0.0043208455
	KFGENEBIN:FLG-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	FLG Gene (Entity type)

SA-1456570
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FLG
Gene (Entity type)
-0.009724473

colforsin-daproate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FLG
Gene (Entity type)
-0.007626442

SID11113856
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FLG
Gene (Entity type)
0.009190929

fentiazac
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FLG
Gene (Entity type)
-0.004246076

7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FLG
Gene (Entity type)
-0.0047177384

2-morpholino-6-(thianthren-1-yl)-4H-pyran-4-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FLG
Gene (Entity type)
-0.0035140328

N20C
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FLG
Gene (Entity type)
-0.005854041

methyl-dopate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FLG
Gene (Entity type)
0.017130766

Ro 40-6055
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FLG
Gene (Entity type)
-0.0043208455

KFGENEBIN:FLG-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
FLG
Gene (Entity type)

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