PPP3CA (Gene)

Entrez Gene ID: 5530

Description: protein phosphatase 3 catalytic subunit alpha

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PPP3CA's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PPP3CA.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PPP3CA.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PPP3CA.

Submit

Gene Sets (3027)

LINCS L1000 Chem Pert Consensus Sigs (761)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (7)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (8)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (748)

A gene set library provided by LINCS

rummageo gene perturbations (173)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (983)

A gene set library provided by LINCS

rummageo chemical perturbations (328)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (15)

A gene set library provided by GTEx

IDG Drug Targets 2022 (4)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Selamectin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PPP3CA Gene (Entity type)	0.0038859139
Biotin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PPP3CA Gene (Entity type)	-0.008617267
L-NAME Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PPP3CA Gene (Entity type)	0.00443604
1-(1-Biphenyl-4-yl-2-phenyl-methyl)-1H-imidazole::1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole (bifonazole)::1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole( Bifanozole)::1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole(Bifonazole)::1-(biphenyl-4-yl-phenyl-methyl)-1H-imidazole::BIFONAZOLE::CHEMBL277535::US9144538, Bifonazole::cid_2378 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PPP3CA Gene (Entity type)	0.0041774646
prothionamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PPP3CA Gene (Entity type)	0.008738323
SA-424170 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PPP3CA Gene (Entity type)	0.012939685
lirimilast Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PPP3CA Gene (Entity type)	0.0042069294
4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,6,7,8,9,10-hexahydro-cycloocta[b]pyridine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PPP3CA Gene (Entity type)	0.005537444
vitexin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PPP3CA Gene (Entity type)	0.008046107
SA-90471 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PPP3CA Gene (Entity type)	-0.011925615

Selamectin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PPP3CA
Gene (Entity type)
0.0038859139

Biotin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PPP3CA
Gene (Entity type)
-0.008617267

L-NAME
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PPP3CA
Gene (Entity type)
0.00443604

1-(1-Biphenyl-4-yl-2-phenyl-methyl)-1H-imidazole::1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole (bifonazole)::1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole( Bifanozole)::1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole(Bifonazole)::1-(biphenyl-4-yl-phenyl-methyl)-1H-imidazole::BIFONAZOLE::CHEMBL277535::US9144538, Bifonazole::cid_2378
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PPP3CA
Gene (Entity type)
0.0041774646

prothionamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PPP3CA
Gene (Entity type)
0.008738323

SA-424170
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PPP3CA
Gene (Entity type)
0.012939685

lirimilast
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PPP3CA
Gene (Entity type)
0.0042069294

4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,6,7,8,9,10-hexahydro-cycloocta[b]pyridine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PPP3CA
Gene (Entity type)
0.005537444

vitexin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PPP3CA
Gene (Entity type)
0.008046107

SA-90471
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PPP3CA
Gene (Entity type)
-0.011925615

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.