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CFDE Workbench

EGF (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:EGF, ENTREZ:1950, HGNC:3229, HOMG4, MIM:131530, NM_001178130, NM_001178131, NM_001357021, NM_001963, NP_001171601, NP_001171602, NP_001343950, NP_001954, URG, XM_005262796, XM_011531707, XM_017007845, XM_017007846, XM_017007847, XM_017007848, XM_017007849, XM_017007850, XM_017007851, XM_017007853, XM_017007854, XM_017007855, XP_005262853, XP_011530009, XP_016863334, XP_016863335, XP_016863336, XP_016863337, XP_016863338, XP_016863339, XP_016863340, XP_016863342, XP_016863343, XP_016863344, XR_001741156, XR_001741157, epidermal growth factor
Omim:OMIM:131530
Nci:C24359
Id:ENSG00000138798
Hgnc:HGNC:3229
Entrez:1950
Ensembl:ENSG00000138798
Description:epidermal growth factor
This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View EGF's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with EGF.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using EGF.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for EGF.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with EGF.

Results found

Linked to

 

Label

Description

 

Gene Set

T61-Colon Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

Gene Set

GSE119424 GSE120214 TBXT brachyury inhibition 7 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE156761 dopamine neuron 0 v 4 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE174745 dopamine neuron 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE156648 DOT1L overexpression IMR-90 2 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE128255 NDP knockdown stem cell 3 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE48812 sulforaphane 4 v 10 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE202434 GSE202438 talazoparib 4 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE102505 tunicamycin 6 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE118939 NRAS knockout 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    T61-Colon Consensus

    Gene Set (Entity type)

    A Gene Set from MoTrPAC

  • Gene Set

    GSE119424 GSE120214 TBXT brachyury inhibition 7 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE156761 dopamine neuron 0 v 4 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE174745 dopamine neuron 1 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE156648 DOT1L overexpression IMR-90 2 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE128255 NDP knockdown stem cell 3 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE48812 sulforaphane 4 v 10 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE202434 GSE202438 talazoparib 4 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE102505 tunicamycin 6 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE118939 NRAS knockout 1 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
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