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CFDE Workbench

VTCN1 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:B7-H4, B7H4, B7S1, B7X, B7h.5, ENTREZ:79679, HGNC:28873, MIM:608162, NM_001253849, NM_001253850, NM_024626, NP_001240778, NP_001240779, NP_078902, NR_045603, NR_045604, PRO1291, V-set domain containing T cell activation inhibitor 1, VCTN1, VTCN1, XM_011542143, XM_017002335, XP_011540445, XP_016857824
Omim:OMIM:608162
Id:ENSG00000134258
Hgnc:HGNC:28873
Entrez:79679
Ensembl:ENSG00000134258
Description:V-set domain containing T cell activation inhibitor 1
This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View VTCN1's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with VTCN1.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using VTCN1.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for VTCN1.

Submit
Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with VTCN1.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE252944 AKT inhibition 7 v 9 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE202434 GSE202438 talazoparib 13 v 11 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE204836 PP-3 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE115542 digoxin 5 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE202434 GSE202438 talazoparib 4 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE80802 EGFR inhibition Tankyrases 0 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE199107 tryptophan 3 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE252944 AKT inhibition 3 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE217452 docetaxel 3 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE202434,GSE202438 13 V 11 TALAZOPARIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE252944 AKT inhibition 7 v 9 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE202434 GSE202438 talazoparib 13 v 11 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE204836 PP-3 1 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE115542 digoxin 5 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE202434 GSE202438 talazoparib 4 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE80802 EGFR inhibition Tankyrases 0 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE199107 tryptophan 3 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE252944 AKT inhibition 3 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE217452 docetaxel 3 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE202434,GSE202438 13 V 11 TALAZOPARIB HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

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    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
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