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CFDE Workbench

CA1 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:CA-I, CA1, CAB, Car1, ENTREZ:759, HEL-S-11, HGNC:1368, MIM:114800, NM_001128829, NM_001128830, NM_001128831, NM_001164830, NM_001291967, NM_001291968, NM_001738, NP_001122301, NP_001122302, NP_001122303, NP_001158302, NP_001278896, NP_001278897, NP_001729, carbonic anhydrase 1
Omim:OMIM:114800
Nci:C183169
Id:ENSG00000133742
Hgnc:HGNC:1368
Entrez:759
Ensembl:ENSG00000133742
Description:carbonic anhydrase 1
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Nov 2016]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CA1's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CA1.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CA1.

Submit
Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CA1.

Submit
Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CA1.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE150895 GSE150896 enzalutamide 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE233679 nicotinamide 14 v 9 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE180321 imperatorin 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Phenotype

Sensorineural hearing impairment

Phenotype (Entity type)

A type of hearing impairment in one or both ears related to an abnormal functionality of the cochlea...

Gene Set

GSE214480 TMIGD2 knockdown HEL-30 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE58724 1 V 0 OXYMETHOLONE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE201309 matrine 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE150895,GSE150896 0 V 1 ENZALUTAMIDE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE160349 IDAM T cell 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE233679 14 V 9 NICOTINAMIDE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE150895 GSE150896 enzalutamide 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE233679 nicotinamide 14 v 9 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE180321 imperatorin 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Phenotype

    Sensorineural hearing impairment

    Phenotype (Entity type)

    A type of hearing impairment in one or both ears related to an abnormal functionality of the cochlea...

  • Gene Set

    GSE214480 TMIGD2 knockdown HEL-30 1 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE58724 1 V 0 OXYMETHOLONE MOUSE DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE201309 matrine 1 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE150895,GSE150896 0 V 1 ENZALUTAMIDE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE160349 IDAM T cell 1 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE233679 14 V 9 NICOTINAMIDE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.