KRAS (Gene)

Entrez Gene ID: 3845

Description: KRAS proto-oncogene, GTPase

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View KRAS's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with KRAS.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using KRAS.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for KRAS.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with KRAS.

Gene Sets (1487)

LINCS L1000 Chem Pert Consensus Sigs (693)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (789)

A gene set library provided by LINCS

IDG Drug Targets 2022 (3)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
DNA-PK inhibitor V Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRAS Gene (Entity type)	-0.0115459245
RVX 208 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRAS Gene (Entity type)	0.0045560566
LY320135 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRAS Gene (Entity type)	-0.004443167
glutamyldopamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRAS Gene (Entity type)	-0.013905935
KFGENEBIN:KRAS-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	KRAS Gene (Entity type)
tremorine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRAS Gene (Entity type)	0.0070732185
N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRAS Gene (Entity type)	-0.0077824634
piceid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRAS Gene (Entity type)	-0.011465041
Cinchocaine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRAS Gene (Entity type)	0.01948242
SAR-245408 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRAS Gene (Entity type)	-0.0036602477

DNA-PK inhibitor V
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRAS
Gene (Entity type)
-0.0115459245

RVX 208
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRAS
Gene (Entity type)
0.0045560566

LY320135
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRAS
Gene (Entity type)
-0.004443167

glutamyldopamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRAS
Gene (Entity type)
-0.013905935

KFGENEBIN:KRAS-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
KRAS
Gene (Entity type)

tremorine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRAS
Gene (Entity type)
0.0070732185

N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRAS
Gene (Entity type)
-0.0077824634

piceid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRAS
Gene (Entity type)
-0.011465041

Cinchocaine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRAS
Gene (Entity type)
0.01948242

SAR-245408
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRAS
Gene (Entity type)
-0.0036602477

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.